


Cararthron®: the new clinically proven natural relief for arthritis
Cararthron® helps provide relief of pain and stiffness associated with osteoarthritis and rheumatoid arthritis. Each capsule contains 250mg UNIVESTIN™‡ a proprietary patented blend of:
- Scutellaria Baicalensis root extract equiv to dry root 2500mg
- Acacia Catechu herb extract dry concentrate equivalent to dry heartwood 715mg

These herbs have both been used traditionally in oriental and ayurvedic medicine for their anti-inflammatory properties.
Cararthron® has been clinically tested and found that regular intake over 4-12 weeks resulted in an improvement of mobility and reduction in stiffness at a level equivalent to that demonstrated by conventional therapies.
This blend of plant extracts has undergone extensive preclinical and clinical testing. Recent randomised double-blind clinical trials confirm the encouraging results from preclinical studies.1,2 This natural product is at least as effective as NSAIDs in helping to reduce the symptoms of arthritis such as pain and stiffness, and increasing mobility.1, 2 Moreover, Cararthron® has an excellent safety profile, and reassuringly the incidence of gastrointestinal (GI) side effects during 3 months was zero.2
In contrast, NSAIDs (e.g. Nurofen®, Celebrex®) may cause GI side effects (e.g. decreased appetite, nausea, vomiting, diarrhoea, constipation, heartburn, stomach pain, cramps).3 These are the most common side effects followed by worsening heart failure or kidney failure, increased blood pressure, increased clotting (thrombosis), dizziness, lightheadedness, tiredness, ringing in the ears and headache, and bleeding.3 Also NSAIDs can cause potentially fatal bleeding from developing ulcers in the gut particularly if you are older than 65 years, had a previous ulcer, are taking warfarin or other medications.3 With Carathron®, the safety profile is excellent and there are minimal interactions with other drugs.1,2
Finally we have a new natural and safe alternative called Cararthron® that works as well as the conventional medicines (e.g. NSAIDs and COX-2 inhibitors) but without the serious side effects. The catechins in Cararthron® are also cardioprotective, so it is reassuring to know that not only will this natural product help to provide relief of pain and stiffness and improvement in overall joint function but there is no compromise to the heart and brain. Cararthron can be taken once or twice a day depending on symptom relief.
Directions for use:
Adults: Take 1 or 2 capsules daily with meals or as directed by your practitioner.
Not suitable for children. Store below 30°C.
- Levy R, et al. Safety and efficacy of flavocoxide compared with naproxen in subjects with osteoarthritis of the knee: a pilot study. Osteoarthr Cartil 2008; 15(suppl B): B91.
- Sampalis JS, et al. Evaluation and comparison of the safety and efficacy of UP446 and celecoxib for the management of pain in patients with osteoarthritis. Data on file, Unigen Pharmaceuticals.
- Arthritis Australia 2009. http://www.rheumatology.org.au/downloads/NSAIDS280509.pdf
‡Univestin™ is a Trade Mark owned by Unigen Inc.
U.S. Patent No. 7,108,868 U.S. Patent No. 7,192,611
Cararthron® is manufactured by Chalmers Dale & Co. Pty Ltd
Suite 1530, 30 Glen St, Milsons Pt., NSW 2061 Australia